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HLA-ABC anticorps

GMP Grade HLA-ABC Reactivité: Humain, Babouin, Cynomolgus, Macaque rhésus FACS Hôte: Souris Monoclonal W6-32 unconjugated
N° du produit ABIN5067844
  • Antigène Voir toutes HLA-ABC Anticorps
    HLA-ABC
    Reactivité
    • 69
    • 23
    • 16
    • 14
    • 13
    • 12
    • 11
    • 11
    • 8
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    Humain, Babouin, Cynomolgus, Macaque rhésus
    Hôte
    • 58
    • 9
    • 3
    Souris
    Clonalité
    • 60
    • 9
    Monoclonal
    Conjugué
    • 31
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HLA-ABC est non-conjugé
    Application
    • 55
    • 17
    • 16
    • 12
    • 11
    • 9
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Fonction
    Anti-HLA-ABC Unconjugated Antibody
    Attributs du produit
    Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
    Purification
    Purified
    Pureté
    >95 %
    Classe de qualité
    GMP Grade
    Immunogène
    Human Leukocytes
    Clone
    W6-32
    Isotype
    IgG2a, kappa
    Top Product
    Discover our top product HLA-ABC Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Antigène
    HLA-ABC
    Autre désignation
    HLA-ABC (HLA-ABC Produits)
    Synonymes
    anticorps HLAA, anticorps major histocompatibility complex, class I, A, anticorps HLA-A
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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