HLA-ABC anticorps
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- Antigène Voir toutes HLA-ABC Anticorps
- HLA-ABC
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Reactivité
- Humain, Babouin, Cynomolgus, Macaque rhésus
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp HLA-ABC est non-conjugé
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Application
- Flow Cytometry (FACS)
- Fonction
- Anti-HLA-ABC Unconjugated Antibody
- Attributs du produit
- Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
- Purification
- Purified
- Pureté
- >95 %
- Classe de qualité
- GMP Grade
- Immunogène
- Human Leukocytes
- Clone
- W6-32
- Isotype
- IgG2a, kappa
- Top Product
- Discover our top product HLA-ABC Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
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- Antigène
- HLA-ABC
- Autre désignation
- HLA-ABC (HLA-ABC Produits)
- Synonymes
- anticorps HLAA, anticorps major histocompatibility complex, class I, A, anticorps HLA-A
- Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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