AADAC anticorps (AA 201-300)

N° du produit ABIN513029

Détail du produit anti-AADAC anticorps

Antigène: AADAC (Arylacetamide Deacetylase (Esterase) (AADAC))

Épitope: AA 201-300

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AADAC est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Mouse monoclonal antibody raised against a partial recombinant AADAC.

Séquence: QLLDDPDVKI KLKIQSLIYP ALQPLDVDLP SYQENSNFLF LSKSLMVRFW SEYFTTDRSL EKAMLSRQHV PVESSHLFKF INWSSLLPER FIKGHVYNNP

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: AADAC (NP_001077, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2E8

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-AADAC (ABIN513029)

Muta, Fukami, Nakajima, Yokoi: "N-Glycosylation during translation is essential for human arylacetamide deacetylase enzyme activity." dans: Biochemical pharmacology, Vol. 87, Issue 2, pp. 352-9, (2014) (PubMed).

Kobayashi, Fukami, Nakajima, Watanabe, Nakajima, Yokoi: "Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 4, pp. 671-9, (2012) (PubMed).

Shimizu, Fukami, Kobayashi, Takamiya, Aoki, Nakajima, Yokoi: "A novel polymorphic allele of human arylacetamide deacetylase leads to decreased enzyme activity." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 6, pp. 1183-90, (2012) (PubMed).

Kobayashi, Fukami, Higuchi, Nakajima, Yokoi: "Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia." dans: Biochemical pharmacology, Vol. 84, Issue 9, pp. 1196-206, (2012) (PubMed).

Watanabe, Fukami, Nakajima, Takamiya, Aoki, Yokoi: "Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 7, pp. 1513-20, (2009) (PubMed).

Détails sur AADAC

Antigène: AADAC (Arylacetamide Deacetylase (Esterase) (AADAC))

Autre désignation: AADAC (AADAC Produits)

Sujet: Full Gene Name: arylacetamide deacetylase (esterase)
Synonyms: CES5A1,DAC

ID gène: 13

NCBI Accession: NM_001086