EIF2AK2 anticorps (AA 1-100)

N° du produit ABIN519273

Détail du produit anti-EIF2AK2 anticorps

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF2AK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Mouse monoclonal antibody raised against a partial recombinant EIF2AK2.

Séquence: MAGDLSAGFF MEELNTYRQK QGVVLKYQEL PNSGPPHDRR FTFQVIIDGR EFPEGEGRSK KEAKNAAAKL AVEILNKEKK AVSPLLLTTT NSSEGLSMGN

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: EIF2AK2 (NP_002750, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1D11

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-EIF2AK2 (ABIN519273)

Liu, Bennett, Cheng, Byrne, Reinhard, May: "PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells." dans: Blood, Vol. 121, Issue 17, pp. 3364-74, (2013) (PubMed).

Cheng, Bennett, Liu, Byrne, Stratford May: "PKR negatively regulates leukemia progression in association with PP2A activation, Bcl-2 inhibition and increased apoptosis." dans: Blood cancer journal, Vol. 3, pp. e144, (2013) (PubMed).

Bennett, Carruthers, Hui, Kerney, Liu, May: "Increased expression of the dsRNA-activated protein kinase PKR in breast cancer promotes sensitivity to doxorubicin." dans: PLoS ONE, Vol. 7, Issue 9, pp. e46040, (2012) (PubMed).

Détails sur EIF2AK2

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Autre désignation: EIF2AK2 (EIF2AK2 Produits)

Synonymes: anticorps PKR, anticorps pkr, anticorps EIF2AK2, anticorps DKFZp469K1934, anticorps EIF2AK1, anticorps PRKR, anticorps 2310047A08Rik, anticorps 4732414G15Rik, anticorps AI467567, anticorps AI747578, anticorps Pkr, anticorps Prkr, anticorps Tik, anticorps eukaryotic translation initiation factor 2 alpha kinase 2, anticorps eukaryotic translation initiation factor 2-alpha kinase 2, anticorps EIF2AK2, anticorps eif2ak2, anticorps Eif2ak2

Sujet: Full Gene Name: eukaryotic translation initiation factor 2-alpha kinase 2
Synonyms: EIF2AK1,MGC126524,PKR,PRKR

ID gène: 5610

NCBI Accession: NM_002759

Pathways: Réparation de l'ADN, ER-Nucleus Signaling, Hepatitis C