TFAM anticorps (AA 1-246)

N° du produit ABIN520832

Détail du produit anti-TFAM anticorps

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Épitope: AA 1-246

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp TFAM est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Mouse polyclonal antibody raised against a full-length human TFAM protein.

Séquence: MAFLRSMWGV LSALGRSGAE LCTGCGSRLR SPFSFVYLPR WFSSVLASCP KKPVSSYLRF SKEQLPIFKA QNPDAKTTEL IRRIAQRWRE LPDSKKKIYQ DAYRAEWQVY KEEISRFKEQ LTPSQIMSLE KEIMDKHLKR KAMTKKKELT LLGKPKRPRS AYNVYVAERF QEAKGDSPQE KLKTVKENWK NLSDSEKELY IQHAKEDETR YHNEMKSWEE QMIEVGRKDL LRRTIKKQRK YGAEEC

Réactivité croisée: Humain

Attributs du produit: Antibody reactive against mammalian transfected lysate.

Immunogène: TFAM (NP_003192.1, 1 a.a. ~ 246 a.a) full-length human protein.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-TFAM (ABIN520832)

Takeda, Hasegawa, Ueha, Sakakibara, Kawamoto, Minamikawa, Sakai, Komori: "Decreased mitochondrial copy numbers in oral squamous cell carcinoma." dans: Head & neck, Vol. 38, Issue 8, pp. 1170-5, (2016) (PubMed).

Morishita, Kawamoto, Hara, Onishi, Ueha, Minoda, Katayama, Takemori, Fukase, Kurosaka, Kuroda, Akisue: "AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway." dans: International journal of oncology, Vol. 50, Issue 1, pp. 23-30, (2016) (PubMed).

Akbari, Sykora, Bohr: "Slow mitochondrial repair of 5'-AMP renders mtDNA susceptible to damage in APTX deficient cells." dans: Scientific reports, Vol. 5, pp. 12876, (2015) (PubMed).

Akbari, Keijzers, Maynard, Scheibye-Knudsen, Desler, Hickson, Bohr: "Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair." dans: DNA repair, Vol. 16, pp. 44-53, (2014) (PubMed).

Gibellini, Pinti, Boraldi, Giorgio, Bernardi, Bartolomeo, Nasi, De Biasi, Missiroli, Carnevale, Losi, Tesei, Pinton, Quaglino, Cossarizza: "Silencing of mitochondrial Lon protease deeply impairs mitochondrial proteome and function in colon cancer cells." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 12, pp. 5122-35, (2014) (PubMed).

Gispert, Parganlija, Klinkenberg, Dröse, Wittig, Mittelbronn, Grzmil, Koob, Hamann, Walter, Büchel, Adler, Hrabé de Angelis, Busch, Zell, Reichert, Brandt, Osiewacz, Jendrach, Auburger: "Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors." dans: Human molecular genetics, Vol. 22, Issue 24, pp. 4871-87, (2013) (PubMed).

Rolland, Motori, Memar, Hench, Frank, Winklhofer, Conradt: "Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 32, pp. E2967-76, (2013) (PubMed).

Holmström, Iglesias-Gutierrez, Zierath, Garcia-Roves: "Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes." dans: American journal of physiology. Endocrinology and metabolism, Vol. 302, Issue 6, pp. E731-9, (2012) (PubMed).

Aamann, Sorensen, Hvitby, Berquist, Muftuoglu, Tian, de Souza-Pinto, Scheibye-Knudsen, Wilson, Stevnsner, Bohr: "Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 7, pp. 2334-46, (2010) (PubMed).

Détails sur TFAM

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Autre désignation: TFAM (TFAM Produits)

Synonymes: anticorps tcf6, anticorps mttf1, anticorps mttfa, anticorps tcf6l1, anticorps tcf6l2, anticorps tcf6l3, anticorps mttfa-A, anticorps xl-mtTFA, anticorps MGC153358, anticorps zgc:153358, anticorps MTTF1, anticorps MTTFA, anticorps TCF6, anticorps TCF6L1, anticorps TCF6L2, anticorps TCF6L3, anticorps AI661103, anticorps Hmgts, anticorps mtTFA, anticorps tsHMG, anticorps Mttfa, anticorps transcription factor A, mitochondrial, anticorps transcription factor A, mitochondrial L homeolog, anticorps TFAM, anticorps tfam.L, anticorps tfam, anticorps Tfam

Sujet: Full Gene Name: transcription factor A, mitochondrial
Synonyms: MtTF1,TCF6,TCF6L1,TCF6L2,TCF6L3,mtTFA

ID gène: 7019

NCBI Accession: NM_003201

Pathways: Chromatin Binding