SQSTM1 anticorps (AA 1-440)
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- Antigène Voir toutes SQSTM1 Anticorps
- SQSTM1 (Sequestosome 1 (SQSTM1))
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Épitope
- AA 1-440
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SQSTM1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Fonction
- Mouse monoclonal antibody raised against a full-length recombinant SQSTM1.
- Séquence
- MASLTVKAYL LGKEDAAREI RRFSFCCSPE PEAEAEAAAG PGPCERLLSR VAALFPALRP GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDHR PPCAQEAPRN MVHPNVICDG CNGPVVGTRY KCSVCPDYDL CSVCEGKGLH RGHTKLAFPS PFGHLSEGFS HSRWLRKVKH GHFGWPGWEM GPPGNWSPRP PRAGEARPGP TAESASGPSE DPSVNFLKNV GESVAAALSP LGIEVDIDVE HGGKRSRLTP VSPESSSTEE KSSSQPSSCC SDPSKPGGNV EGATQSLAEQ MRKIALESEG RPEEQMESDN CSGGDDDWTH LSSKEVDPST GELQSLQMPE SEGPSSLDPS QEGPTGLKEA ALYPHLPPEA DPRLIESLSQ MLSMGFSDEG GWLTRLLQTK NYDIGAALDT IQYSKHPPPL
- Réactivité croisée
- Humain
- Attributs du produit
- Antibody Reactive Against Recombinant Protein.
- Immunogène
- SQSTM1 (AAH03139.1, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Clone
- 1C9
- Isotype
- IgG3
- Top Product
- Discover our top product SQSTM1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- In 1x PBS, pH 7.4
- Conseil sur la manipulation
- Aliquot to avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling." dans: Nature medicine, Vol. 22, Issue 1, pp. 46-53, (2016) (PubMed).
: "Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation." dans: Cell death & disease, Vol. 4, pp. e638, (2013) (PubMed).
: "BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway." dans: Biochemical pharmacology, Vol. 80, Issue 8, pp. 1160-9, (2010) (PubMed).
: "A role for NBR1 in autophagosomal degradation of ubiquitinated substrates." dans: Molecular cell, Vol. 33, Issue 4, pp. 505-16, (2009) (PubMed).
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Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling." dans: Nature medicine, Vol. 22, Issue 1, pp. 46-53, (2016) (PubMed).
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- Antigène
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Autre désignation
- SQSTM1 (SQSTM1 Produits)
- Synonymes
- anticorps SQSTM1, anticorps sqstm1, anticorps MGC79491, anticorps A170, anticorps OSIL, anticorps PDB3, anticorps ZIP3, anticorps p60, anticorps p62, anticorps p62B, anticorps OSF-6, anticorps Osi, anticorps STAP, anticorps ZIP, anticorps sb:cb621, anticorps zgc:85784, anticorps sequestosome 1, anticorps sequestosome 1 L homeolog, anticorps SQSTM1, anticorps sqstm1, anticorps Sqstm1, anticorps sqstm1.L
- Sujet
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Full Gene Name: sequestosome 1
Synonyms: A170,OSIL,PDB3,ZIP3,p60,p62,p62B - ID gène
- 8878
- Pathways
- Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy
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