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DERL1 anticorps (C-Term)
DERL1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5515996
Détail du produit anti-DERL1 anticorps
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Antigène
Voir toutes DERL1 Anticorps
DERL1
(Der1-Like Domain Family, Member 1 (DERL1))
Épitope
Tous les épitopes à travers DERL1 Anticorps.
C-Term
Reactivité
Toutes les réactivités sur DERL1 Anticorps
Humain
Hôte
Toutes les hôtes sur DERL1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur DERL1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers DERL1 Anticorps
Cet anticorp DERL1 est non-conjugé
Application
Tous les applications à travers DERL1 Anticorps.
Western Blotting (WB)
Séquence
STPQFLYRWL PSRRGGVSGF GVPPASMRRA ADQNGGGGRH NWGQGFRLGD
Attributs du produit
This is a rabbit polyclonal antibody against DERL1. It was validated on Western Blot.
Purification
Affinity Purified
Immunogène
The immunogen is a synthetic peptide directed towards the C-terminal region of Human DERL1
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur DERL1
(cache)
Antigène
DERL1
(Der1-Like Domain Family, Member 1 (DERL1))
Autre désignation
DERL1 (DERL1 Produits )
Synonymes
anticorps CG10908, anticorps Dmel\\CG10908, anticorps DDBDRAFT_0188135, anticorps DDBDRAFT_0266772, anticorps DDB_0188135, anticorps DDB_0266772, anticorps MGC84200, anticorps wu:fb09d07, anticorps wu:fb94d05, anticorps wu:fj92g12, anticorps zgc:55637, anticorps 1110021N07Rik, anticorps AI195141, anticorps AW551338, anticorps Derlin-1, anticorps derlin-1, anticorps DER-1, anticorps DER1, anticorps RGD1311835, anticorps DERLIN-1, anticorps F17A13.150, anticorps F17A13_150, anticorps Derlin-1, anticorps derlin-1, anticorps derlin-1.1, anticorps hypothetical protein, anticorps Der1-like domain family, member 1, anticorps derlin 1, anticorps derlin 1 L homeolog, anticorps DERLIN-1, anticorps Der-1, anticorps EDI_023440, anticorps PTRG_01331, anticorps derl1, anticorps DERL1, anticorps derl1.L, anticorps Derl1, anticorps DER1
Sujet
The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. Alias Symbols: DERL1, DER1, UNQ243/PRO276, Protein Interaction Partner: HM13, TCF25, XBP1, EGFR, USP19, ZFAND2B, Vcp, PTGS2, CAV1, SYVN1, DERL2, SHH, SEL1L, SERPINA1, FAF2, ALB, APP, DERL1, EDEM1, RNF5, RHO, NGLY1, BCAP31, CFTR, UBXN6, TRAM1, APOB, CLN6, UBXN4, ERN1, ASGR2, UBE2J1, ERLIN2, UBC, HLA-A, CACNA1C, YOD1, VIMP, KPN Protein Size: 251
ID gène
79139
NCBI Accession
NP_077271
UniProt
Q9BUN8
Pathways
ER-Nucleus Signaling
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