×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
MAPK8IP1 anticorps (Middle Region)
MAPK8IP1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5516520
Détail du produit anti-MAPK8IP1 anticorps
(cache)
Antigène
Voir toutes MAPK8IP1 Anticorps
MAPK8IP1
(Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
Épitope
Tous les épitopes à travers MAPK8IP1 Anticorps.
Middle Region
Reactivité
Toutes les réactivités sur MAPK8IP1 Anticorps
Humain
Hôte
Toutes les hôtes sur MAPK8IP1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur MAPK8IP1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers MAPK8IP1 Anticorps
Cet anticorp MAPK8IP1 est non-conjugé
Application
Tous les applications à travers MAPK8IP1 Anticorps.
Western Blotting (WB)
Séquence
VPRSQDTLNN NSLGKKHSWQ DRVSRSSSPL KTGEQTPPHE HICLSDELPP
Purification
Affinity purified
Immunogène
The immunogen is a synthetic peptide directed towards the middle region of human MAPK8IP1
Top Product
Discover our top product MAPK8IP1 Anticorps primaire
Alternatives
(show)
Information d'application
(cache)
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur MAPK8IP1
(cache)
Antigène
MAPK8IP1
(Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
Autre désignation
MAPK8IP1 (MAPK8IP1 Produits )
Synonymes
anticorps IB1, anticorps JIP-1, anticorps Jip1, anticorps Prkm8ip, anticorps Skip, anticorps mjip-2a, anticorps JIP1, anticorps Jip-1, anticorps Mapk8ip, anticorps PRKM8IP, anticorps mitogen-activated protein kinase 8 interacting protein 1, anticorps MAPK8IP1, anticorps Mapk8ip1
Sujet
This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. Alias Symbols: IB1, JIP1, JIP-1, PRKM8IP Protein Size: 711
ID gène
9479
NCBI Accession
NM_005456 , NP_005447
UniProt
Q9UQF2
Vus récemment
(cache)