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KIDINS220 anticorps (Middle Region)
KIDINS220
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5516661
Détail du produit anti-KIDINS220 anticorps
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Antigène
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KIDINS220
(Kinase D-Interacting Substrate, 220kDa (KIDINS220))
Épitope
Tous les épitopes à travers KIDINS220 Anticorps.
Middle Region
Reactivité
Toutes les réactivités sur KIDINS220 Anticorps
Humain
Hôte
Toutes les hôtes sur KIDINS220 Anticorps
Lapin
Clonalité
Toutes les clonalités sur KIDINS220 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers KIDINS220 Anticorps
Cet anticorp KIDINS220 est non-conjugé
Application
Tous les applications à travers KIDINS220 Anticorps.
Western Blotting (WB)
Séquence
VERVPKSPEH SAEPIRTFIK AKEYLSDALL DKKDSSDSGV RSSESSPNHS
Homologie
Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 93%
Purification
Affinity purified
Immunogène
The immunogen is a synthetic peptide directed towards the middle region of human KIDINS220
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur KIDINS220
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Antigène
KIDINS220
(Kinase D-Interacting Substrate, 220kDa (KIDINS220))
Autre désignation
KIDINS220 (KIDINS220 Produits )
Synonymes
anticorps ARMS, anticorps fj35h03, anticorps kidins220, anticorps zgc:63531, anticorps dZ119J18.2, anticorps wu:fj35h03, anticorps 3110039L19Rik, anticorps AI194387, anticorps AI316525, anticorps C330002I19Rik, anticorps mKIAA1250, anticorps kinase D interacting substrate 220, anticorps kinase D-interacting substrate 220, anticorps kinase D-interacting substrate 220b, anticorps kinase D-interacting substrate 220kDa, anticorps KIDINS220, anticorps Kidins220, anticorps kidins220b
Sujet
Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration. Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway. Alias Symbols: ARMS Protein Interaction Partner: UBC, LGR4, MYC, FN1, MOB4, CDC73, PRKD1, CRKL, NTRK2, NTRK3, NTRK1, NGFR, Protein Size: 59
Poids moléculaire
543 kDa
ID gène
57498
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