GPR31 anticorps (C-Term)

N° du produit ABIN5516748

Détail du produit anti-GPR31 anticorps

Antigène: GPR31 (G Protein-Coupled Receptor 31 (GPR31))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR31 est non-conjugé

Application: Western Blotting (WB)

Séquence: QKRLREPEKQ PKLQRAQALV TLVVVLFALC FLPCFLARVL MHIFQNLGSC

Attributs du produit: This is a rabbit polyclonal antibody against GPR31. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GPR31

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GPR31

Antigène: GPR31 (G Protein-Coupled Receptor 31 (GPR31))

Autre désignation: GPR31 (GPR31 Produits)

Synonymes: anticorps 12-HETER, anticorps HETER, anticorps HETER1, anticorps GPR31, anticorps GPR31c(t), anticorps Gpr31, anticorps Gpr31c, anticorps G protein-coupled receptor 31, anticorps G protein-coupled receptor 31, D17Leh66b region, anticorps GPR31, anticorps Gpr31, anticorps Gpr31b

Sujet: GPR31 is a high-affinity receptor for 12-(S)-hydroxy-5,8,10,14- eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.

Alias Symbols: GPR31,

Protein Size: 319

ID gène: 2853

NCBI Accession: NP_005290

UniProt: O00270