GZMH anticorps (C-Term)

N° du produit ABIN5516766

Détail du produit anti-GZMH anticorps

Antigène: GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GZMH est non-conjugé

Application: Western Blotting (WB)

Séquence: EVLLTVQKDC QCERLFHGNY SRATEICVGD PKKTQTGFKG DSGGPLVCKD

Attributs du produit: This is a rabbit polyclonal antibody against GZMH. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GZMH

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GZMH

Antigène: GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))

Autre désignation: GZMH (GZMH Produits)

Synonymes: anticorps GZMH, anticorps CCP-X, anticorps CGL-2, anticorps CSP-C, anticorps CTLA1, anticorps CTSGL2, anticorps granzyme H, anticorps LOC617313, anticorps GZMH

Sujet: The protein encoded by this gene is a member of the granzyme family. Members of this family are highly conserved serine proteases that eliminate transformed cells and virus-infected cells. This protein, which has chymotrypsin-like activity, has a preference for bulky aromatic amino acids at the P1 position and for acidic residues at the P3' and P4' positions. This protein is reported to be constitutively expressed in NK cells and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Alias Symbols: GZMH, CGL2, CTSGL2,

Protein Interaction Partner: SSB,

Protein Size: 246

ID gène: 2999

NCBI Accession: NP_219491

UniProt: P20718