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FBXL15 anticorps (N-Term)

FBXL15 Reactivité: Humain, Souris, Lapin, Rat, Boeuf (Vache), Chien, Chévre, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5517039
  • Antigène Voir toutes FBXL15 Anticorps
    FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))
    Épitope
    • 7
    • 7
    • 6
    N-Term
    Reactivité
    Humain, Souris, Lapin, Rat, Boeuf (Vache), Chien, Chévre, Cheval
    Hôte
    • 14
    Lapin
    Clonalité
    • 14
    Polyclonal
    Conjugué
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp FBXL15 est non-conjugé
    Application
    • 14
    • 13
    • 12
    • 1
    Western Blotting (WB)
    Séquence
    PPMEPSGGEQ EPGAVRFLDL PWEDVLLPHV LNRVPLRQLL RLQRVSRAFR
    Homologie
    Cow: 93%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against FBXL15. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15
    Top Product
    Discover our top product FBXL15 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))
    Autre désignation
    FBXL15 (FBXL15 Produits)
    Synonymes
    anticorps 0710008C12Rik, anticorps Fbxo37, anticorps RGD1306444, anticorps fbl15, anticorps fbxo37, anticorps FBXO37, anticorps Fbl15, anticorps JET, anticorps PSD, anticorps F4I10.140, anticorps F4I10_140, anticorps SLOW MOTION, anticorps fbxl15, anticorps zgc:85882, anticorps F-box and leucine-rich repeat protein 15, anticorps F-box and leucine-rich repeat protein 15 L homeolog, anticorps F-box and leucine rich repeat protein 15, anticorps F-box family protein, anticorps F-box only protein 37, anticorps Fbxl15, anticorps fbxl15.L, anticorps FBXL15, anticorps fbxl15, anticorps SLOMO, anticorps fbx37
    Sujet
    FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.

    Alias Symbols: FBXO37, Fbl15, JET, PSD

    Protein Interaction Partner: HNRNPD, SKP1, ITCH, SMURF2, HECW2, SMURF1, NEDD4L, HECW1, WWP2, WWP1, RBX1, CUL1, NEDD4, HSP90AA1, COPS6, UBC,

    Protein Size: 300
    ID gène
    79176
    NCBI Accession
    NM_024326, NP_077302
    UniProt
    Q9H469
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