FBXL15 anticorps (N-Term)

N° du produit ABIN5517039

Détail du produit anti-FBXL15 anticorps

Antigène: FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))

Épitope: N-Term

Reactivité: Humain, Boeuf (Vache), Chien, Chévre, Cheval, Souris, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXL15 est non-conjugé

Application: Western Blotting (WB)

Séquence: PPMEPSGGEQ EPGAVRFLDL PWEDVLLPHV LNRVPLRQLL RLQRVSRAFR

Homologie: Cow: 93%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FBXL15. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FBXL15

Antigène: FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))

Autre désignation: FBXL15 (FBXL15 Produits)

Synonymes: anticorps 0710008C12Rik, anticorps Fbxo37, anticorps RGD1306444, anticorps fbl15, anticorps fbxo37, anticorps FBXO37, anticorps Fbl15, anticorps JET, anticorps PSD, anticorps F4I10.140, anticorps F4I10_140, anticorps SLOW MOTION, anticorps fbxl15, anticorps zgc:85882, anticorps F-box and leucine-rich repeat protein 15, anticorps F-box and leucine-rich repeat protein 15 L homeolog, anticorps F-box and leucine rich repeat protein 15, anticorps F-box family protein, anticorps F-box only protein 37, anticorps Fbxl15, anticorps fbxl15.L, anticorps FBXL15, anticorps fbxl15, anticorps SLOMO, anticorps fbx37

Sujet: FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.

Alias Symbols: FBXO37, Fbl15, JET, PSD

Protein Interaction Partner: HNRNPD, SKP1, ITCH, SMURF2, HECW2, SMURF1, NEDD4L, HECW1, WWP2, WWP1, RBX1, CUL1, NEDD4, HSP90AA1, COPS6, UBC,

Protein Size: 300

ID gène: 79176

NCBI Accession: NM_024326, NP_077302

UniProt: Q9H469