PKDCC anticorps (N-Term)

N° du produit ABIN5517602

Détail du produit anti-PKDCC anticorps

Antigène: PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKDCC est non-conjugé

Application: Western Blotting (WB)

Séquence: GGRGELARQI RARYEEVQRY SRGGPGPGAG RPERRRLMDL APGGPGLPRP

Homologie: Cow: 100%, Dog: 78%, Human: 100%, Mouse: 100%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PKDCC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PKDCC

Antigène: PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))

Autre désignation: PKDCC (PKDCC Produits)

Synonymes: anticorps SGK493, anticorps Vlk, anticorps AI115348, anticorps AW548124, anticorps Adtk1, anticorps ESTM17, anticorps MAd1, anticorps Sgk493, anticorps X83346, anticorps RGD1311939, anticorps protein kinase domain containing, cytoplasmic, anticorps PKDCC, anticorps Pkdcc

Sujet: Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29. Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation. May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation. May be indirectly involved in protein transport from the Golgi apparatus to the plasma membrane.

Alias Symbols: Vlk, SGK493

Protein Size: 493

ID gène: 91461

NCBI Accession: NM_138370, NP_612379

UniProt: Q504Y2