THOC7 anticorps (C-Term)

N° du produit ABIN5517619

Détail du produit anti-THOC7 anticorps

Antigène: THOC7 (THO Complex 7 (THOC7))

Épitope: C-Term

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp THOC7 est non-conjugé

Application: Western Blotting (WB)

Séquence: SVEDKLELRR KQFHVLLSTI HELQQTLEND EKLSEVEEAQ EASMETDPKP

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 79%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against THOC7. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human THOC7

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur THOC7

Antigène: THOC7 (THO Complex 7 (THOC7))

Autre désignation: THOC7 (THOC7 Produits)

Synonymes: anticorps RGD1305475, anticorps NIF3L1BP1, anticorps fSAP24, anticorps 1500006O09Rik, anticorps 9230101K24Rik, anticorps Nif3l1bp1, anticorps THO complex 7, anticorps Thoc7, anticorps THOC7

Sujet: THOC7 is required for efficient export of polyadenylated RNA. It acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.

Alias Symbols: THOC7, NIF3L1BP1,

Protein Interaction Partner: THOC2, RPA3, RPA2, RPA1, CKAP4, UBC, ZC3H15, TRMT112, PPIP5K2, THOC1, UBE3C, USP13, ZPR1, THOC5, VIM, S100A13, WDR36, ZCRB1, THOC3, ZNF606, THOC6, ALYREF, DDX39B, NIF3L1, CHD3, MED8, GOT2, MED18, MED22,

Protein Size: 204

ID gène: 80145

NCBI Accession: NP_079351

UniProt: Q6I9Y2