GSAP anticorps (N-Term)

N° du produit ABIN5517988

Détail du produit anti-GSAP anticorps

Antigène: GSAP (PION) (Pigeon Homolog (PION))

Épitope: N-Term

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSAP est non-conjugé

Application: Western Blotting (WB)

Séquence: QTRQNELLYT FEKDLQVFSC SVNSERTLLA ASLVQSTKEG KRNELQPGSK

Homologie: Cow: 85%, Dog: 85%, Horse: 93%, Human: 100%, Rabbit: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against GSAP. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GSAP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GSAP

Antigène: GSAP (PION) (Pigeon Homolog (PION))

Autre désignation: GSAP (PION Produits)

Synonymes: anticorps PION, anticorps A530088I07Rik, anticorps Pion, anticorps gamma-secretase activating protein, anticorps GSAP, anticorps Gsap

Sujet: Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease. Formation of amyloid-beta is catalyzed by gamma-secretase, a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein C-terminal fragment (APP-CTF).

Alias Symbols: GSAP, PION,

Protein Size: 854

ID gène: 54103

NCBI Accession: NP_059135

UniProt: A4D1B5