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DENND3 anticorps (C-Term)

DENND3 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5518005
  • Antigène Tous les produits DENND3
    DENND3 (DENN/MADD Domain Containing 3 (DENND3))
    Épitope
    C-Term
    Reactivité
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 2
    Lapin
    Clonalité
    • 2
    Polyclonal
    Conjugué
    • 2
    Cet anticorp DENND3 est non-conjugé
    Application
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    INCMIRVKKQ VWVGSRGLGQ GTPKGKIYVI DAERKTVEKE LVAHMDTVRT
    Attributs du produit
    This is a rabbit polyclonal antibody against DENND3. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND3
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    DENND3 (DENN/MADD Domain Containing 3 (DENND3))
    Autre désignation
    DENND3 (DENND3 Produits)
    Synonymes
    anticorps AI447457, anticorps E030003N15Rik, anticorps DENN domain containing 3, anticorps DENN/MADD domain containing 3, anticorps DENND3, anticorps Dennd3
    Sujet
    DENND3 is a guanine nucleotide exchange factor (GEF) activating RAB12. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, DENND3 may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.

    Alias Symbols: DENND3, KIAA0870,

    Protein Interaction Partner: UBC, YAP1,

    Protein Size: 1146
    ID gène
    22898
    NCBI Accession
    NP_055772
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