CD147 anticorps (AA 138-323)

N° du produit ABIN5518743

Détail du produit anti-CD147 anticorps

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Épitope: AA 138-323

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD147 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Basigin(BSG) detection. Tested with WB, IHC-P, FCM in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Basigin(BSG) detection. Tested with WB, IHC-P, FCM in Human,Mouse,Rat.
Gene Name: basigin (Ok blood group)
Protein Name: Basigin

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CD147/Emmprin recombinant protein (Position: E138-A323). Human CD147/Emmprin shares 51.1% and 51.9% amino acid (aa) sequence identity with mouse and rat CD147/Emmprin, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Flow Cytometry: Concentration: 1-3 μg/1x106 cells, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-CD147 (ABIN5518743)

Zhang, Yang, Liu, Liu, Teng, Zhang, Yin, Liu et al.: "iTRAQ-coupled 2D LC/MS-MS analysis of CXCR7-transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of ..." dans: Oncology letters, Vol. 14, Issue 3, pp. 3734-3740, (2017) (PubMed).

Xiao, Zhao, Shen, Liang, Chen: "Overexpression of CD147 is associated with poor prognosis, tumor cell migration and ERK signaling pathway activation in hepatocellular carcinoma." dans: Experimental and therapeutic medicine, Vol. 14, Issue 3, pp. 2637-2642, (2017) (PubMed).

Lu, Lv, Kim, Ha, Kim: "Expression and clinical significance of extracellular matrix metalloproteinase inducer, EMMPRIN/CD147, in human osteosarcoma." dans: Oncology letters, Vol. 5, Issue 1, pp. 201-207, (2012) (PubMed).

Détails sur CD147

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Autre désignation: BSG (BSG Produits)

Synonymes: anticorps EMMPRIN, anticorps RPE7, anticorps 5F7, anticorps CD147, anticorps M6, anticorps OK, anticorps TCSF, anticorps AI115436, anticorps AI325119, anticorps HT-7, anticorps 5A11, anticorps CE9, anticorps HT7, anticorps Ox47R, anticorps basignin, anticorps wu:fb26a05, anticorps wu:fo98e12, anticorps bsg, anticorps prso03, anticorps basigin (Ok blood group), anticorps basigin, anticorps basigin (Ok blood group) S homeolog, anticorps BSG, anticorps Bsg, anticorps bsg, anticorps bsg.S

Sujet: Emmprin, extracellular matrix metalloproteinase inducer, also known as Emmprin (BSG) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the Emmprin gene. The human BSG gene is mapped to 19p13.3. This protein is a determinant for the Ok blood group system. BSG has been shown to be an essential receptor on red blood cells for the malaria parasite. It is a member of the immunoglobulin superfamily, with a structure related to the putative primordial form of the family. As members of the immunoglobulin superfamily, it plays fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development. BSG is thought also to play a role in intercellular recognition. It also regulates several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. BSG is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins. It is expressed by many cell types, including epithelial cells, endothelial cells and leukocytes.

Synonyms: 5A11 antigen | 5F7 | BASI | Basigin | basigin (Ok blood group) | Basigin(Ok blood group) | BSG | CD147 antigen | Collagenase stimulatory factor | Emmprin | HT7 antigen | Leukocyte activation antigen M6 | neurothelin | OK blood group antigen | OX-47 antigen | P35613 | TCSF

ID gène: 682

UniProt: P35613

Pathways: S100 Proteins