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IL-13 anticorps (AA 36-146)

IL13 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5518763
  • Antigène Voir toutes IL-13 (IL13) Anticorps
    IL-13 (IL13) (Interleukin 13 (IL13))
    Épitope
    • 15
    • 10
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 36-146
    Reactivité
    • 92
    • 38
    • 31
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 78
    • 25
    • 23
    • 2
    • 2
    Lapin
    Clonalité
    • 82
    • 48
    Polyclonal
    Conjugué
    • 69
    • 18
    • 9
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-13 est non-conjugé
    Application
    • 84
    • 66
    • 32
    • 18
    • 17
    • 15
    • 13
    • 13
    • 10
    • 10
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for Interleukin-13(IL13) detection. Tested with WB, IHC-P in Human.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Interleukin-13(IL13) detection. Tested with WB, IHC-P in Human.
    Gene Name: interleukin 13
    Protein Name: Interleukin-13
    Purification
    Immunogen affinity purified.
    Immunogène
    E. coli-derived human IL13 recombinant protein (Position: P36-N146). Human IL13 shares 55.3% and 61.9% amino acid (aa) sequence identity with mouse and rat IL13, respectively.
    Isotype
    IgG
    Top Product
    Discover our top product IL13 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Liu, Wang, Cao, Liu, Zou, Li, Yang, Jiao: "Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 3674145, (2018) (PubMed).

    Zhu, Li, Wu, Lu, You, Li, Li, Yang, Duan: "Acute exposure of ozone induced pulmonary injury and the protective role of vitamin E through the Nrf2 pathway in Balb/c mice." dans: Toxicology research, Vol. 5, Issue 1, pp. 268-277, (2018) (PubMed).

    Li, Zhang, Qin, Bi, Liu, Li, Cai, Ma, Chan, Xie, Guan: "CD68 and interleukin 13, prospective immune markers for esophageal squamous cell carcinoma prognosis prediction." dans: Oncotarget, Vol. 7, Issue 13, pp. 15525-38, (2017) (PubMed).

    Wang, Liang, Wang, Zhu, Gong, Zhang, Li, Xia: "Th17 down-regulation is involved in reduced progression of schistosomiasis fibrosis in ICOSL KO mice." dans: PLoS neglected tropical diseases, Vol. 9, Issue 1, pp. e0003434, (2016) (PubMed).

    Long, Chen, Zhao, Rafaels, Mathias, Liang, Potee, Campbell, Zhang, Gao, Georas, Vercelli, Beaty, Ruczinski, Mathias, Barnes, Chen: "An IL-13 promoter polymorphism associated with liver fibrosis in patients with Schistosoma japonicum." dans: PLoS ONE, Vol. 10, Issue 8, pp. e0135360, (2016) (PubMed).

  • Antigène
    IL-13 (IL13) (Interleukin 13 (IL13))
    Autre désignation
    IL13 (IL13 Produits)
    Synonymes
    anticorps IL13, anticorps IL-13, anticorps P600, anticorps Il-13, anticorps L13, anticorps interleukin 13, anticorps IL13, anticorps Il13
    Sujet
    Interleukin 13 is a protein that in humans is encoded by the IL-13 gene. It is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. Furthermore, this gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

    Synonyms: ALRH | IL 13 | IL13 | IL-13 | il13ra2 | interleukin 13 | Interleukin13 | Interleukin-13 | Interleukin13(IL13) | Interleukin-13(IL-13) | NC30
    ID gène
    3596
    UniProt
    P35225
    Pathways
    Signalistation JAK/STAT, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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