NOS2 anticorps (C-Term)
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- Antigène Voir toutes NOS2 Anticorps
- NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
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Épitope
- AA 1088-1126, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NOS2 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- Rabbit IgG polyclonal antibody for Nitric oxide synthase, inducible(NOS2) detection. Tested with WB in Human.
- Séquence
- ARDVAHTLKQ LVAAKLKLNE EQVEDYFFQL KSQKRYHED
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Nitric oxide synthase, inducible(NOS2) detection. Tested with WB in Human.
Gene Name: nitric oxide synthase 2, inducible
Protein Name: Nitric oxide synthase, inducible - Purification
- Immunogen affinity purified.
- Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human iNOS (1088-1126aa ARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHED), different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product NOS2 Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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[Corrigendum] Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." dans: Molecular medicine reports, Vol. 17, Issue 5, pp. 6926, (2018) (PubMed).
: "Esculentoside A ameliorates cecal ligation and puncture-induced acute kidney injury in rats." dans: Experimental animals, (2017) (PubMed).
: "Intermittent hypoxia simulating obstructive sleep apnea causes pulmonary inflammation and activates the Nrf2/HO-1 pathway." dans: Experimental and therapeutic medicine, Vol. 14, Issue 4, pp. 3463-3470, (2017) (PubMed).
: "Detecting cell-in-cell structures in human tumor samples by E-cadherin/CD68/CD45 triple staining." dans: Oncotarget, Vol. 6, Issue 24, pp. 20278-87, (2016) (PubMed).
: "Celastrol Ameliorates Ulcerative Colitis-Related Colorectal Cancer in Mice via Suppressing Inflammatory Responses and Epithelial-Mesenchymal Transition." dans: Frontiers in pharmacology, Vol. 6, pp. 320, (2016) (PubMed).
: "Higher activity of the inducible nitric oxide synthase contributes to very early onset inflammatory bowel disease." dans: Clinical and translational gastroenterology, Vol. 5, pp. e46, (2014) (PubMed).
: "Atmospheric pressure room temperature plasma jets facilitate oxidative and nitrative stress and lead to endoplasmic reticulum stress dependent apoptosis in HepG2 cells." dans: PLoS ONE, Vol. 8, Issue 8, pp. e73665, (2013) (PubMed).
: "The hypoglycemic effect of the kelp on diabetes mellitus model induced by alloxan in rats." dans: International journal of molecular sciences, Vol. 13, Issue 3, pp. 3354-65, (2012) (PubMed).
: "Cell-specific expression and immunolocalization of nitric oxide synthase isoforms and the related nitric oxide/cyclic GMP signaling pathway in the ovaries of neonatal and immature rats." dans: Journal of Zhejiang University. Science. B, Vol. 12, Issue 1, pp. 55-64, (2011) (PubMed).
: "Z-ligustilide attenuates lipopolysaccharide-induced proinflammatory response via inhibiting NF-kappaB pathway in primary rat microglia." dans: Acta pharmacologica Sinica, Vol. 31, Issue 7, pp. 791-7, (2010) (PubMed).
: "Inhibition by brimonidine of forskolin-induced nitric oxide synthase expression in human ciliary bodies in vitro." dans: Molecular vision, Vol. 13, pp. 493-6, (2007) (PubMed).
: "Expressions of inducible nitric oxide synthase and matrix metalloproteinase-9 and their effects on angiogenesis and progression of hepatocellular carcinoma." dans: World journal of gastroenterology, Vol. 11, Issue 38, pp. 5931-7, (2006) (PubMed).
: "Anti-cancer effect of iNOS inhibitor and its correlation with angiogenesis in gastric cancer." dans: World journal of gastroenterology, Vol. 11, Issue 25, pp. 3830-3, (2005) (PubMed).
: "Role of inducible nitric oxide synthase expression in aberrant crypt foci-adenoma-carcinoma sequence." dans: World journal of gastroenterology, Vol. 9, Issue 6, pp. 1246-50, (2003) (PubMed).
: "[Implantation of a Binkhorst lens in chronic simple glaucoma]." dans: Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, Vol. 82, Issue 2, pp. 186, (1985) (PubMed).
: "Portrait of a pioneer laryngologist." dans: Eye, ear, nose & throat monthly, Vol. 53, Issue 11, pp. 460-4, (1975) (PubMed).
: "Diseases of the dermis. General considerations." dans: Archives belges de dermatologie et de syphiligraphie, Vol. 28, Issue 1, pp. 1-13, (1973) (PubMed).
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[Corrigendum] Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." dans: Molecular medicine reports, Vol. 17, Issue 5, pp. 6926, (2018) (PubMed).
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- Antigène
- NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
- Autre désignation
- NOS2 (NOS2 Produits)
- Synonymes
- anticorps HEP-NOS, anticorps INOS, anticorps NOS, anticorps NOS2A, anticorps NOS-II, anticorps Nos-2, anticorps Nos2a, anticorps i-NOS, anticorps iNOS, anticorps iNos, anticorps NOS2a, anticorps NOS2, anticorps BmNOS2, anticorps Nsl, anticorps nos2, anticorps nitric oxide synthase 2, anticorps nitric oxide synthase 2, inducible, anticorps inducible nitric oxide synthase, anticorps inducible nitric-oxide synthase, anticorps nanos C2HC-type zinc finger 2, anticorps NOS2, anticorps Nos2, anticorps nos2, anticorps LOC396821, anticorps NANOS2
- Sujet
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Nitric oxide synthase, inducible is an enzyme that in humans is encoded by the NOS2 gene. Nitric oxide (NO) is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter, it is implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. Three different NOS isoforms have been identified which fall into two distinct types, constitutive and inducible. The inducible NOS (iNOS) isoform is expressed in a variety of cell types and tissues in response to inflammatory agents and cytokines. The human iNOS (NOS2) gene is approximately 37 kb in length and consists of 26 exons and 25 introns. NOS2-derived NO is a prerequisite for cytokine signaling and function in innate immunity.
Synonyms: Ascites | HEP NOS | Hepatocyte NOS | HEPNOS | HEP-NOS | Inducible NOS | iNOS | NANOS2 | nitric oxide synthase 2, inducible | NOS 2A | NOS2A | P60321 - ID gène
- 4843
- UniProt
- P35228
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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