RPS6 anticorps (N-Term)

N° du produit ABIN5518869

Détail du produit anti-RPS6 anticorps

Antigène: RPS6 (Ribosomal Protein S6 (RPS6))

Épitope: AA 13-52, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPS6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for 40S ribosomal protein S6(RPS6) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: QKLIEVDDER KLRTFYEKRM ATEVAADALG EEWKGYVVRI

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for 40S ribosomal protein S6(RPS6) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: ribosomal protein S6
Protein Name: 40S ribosomal protein S6

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human RPS6 (13-52aa QKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRI), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur RPS6

Antigène: RPS6 (Ribosomal Protein S6 (RPS6))

Autre désignation: RPS6 (RPS6 Produits)

Synonymes: anticorps S6, anticorps rps6, anticorps rps6a, anticorps S6R, anticorps (Rp)S6, anticorps CG10944, anticorps DS6, anticorps Dmel\\CG10944, anticorps M(1)7BC, anticorps M(1)7C, anticorps RPS6, anticorps Rp S6, anticorps Rps6, anticorps air8, anticorps air[8], anticorps anon-WO02059370.61, anticorps hen, anticorps l(1)air8, anticorps l(1)air[8], anticorps l(1)hen, anticorps pp30, anticorps rpS6, anticorps wu:fa92e06, anticorps wu:fb64g06, anticorps zgc:92237, anticorps ribosomal protein S6, anticorps ribosomal protein S6 S homeolog, anticorps S6 ribosomal protein, anticorps Ribosomal protein S6, anticorps 30S ribosomal protein S6, anticorps 40S ribosomal protein S6, anticorps RPS6, anticorps rps6.S, anticorps LOC100135859, anticorps Rps6, anticorps RpS6, anticorps rps6, anticorps rps-6, anticorps LOC100533219

Sujet: Ribosomal protein S6 (rpS6) is a component of the 40S ribosomal subunit and is therefore thought to be involved in regulating translation. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. While the true function of rpS6 is currently under investigation, studies have shown that it is involved in the regulation of cell size, cell proliferation, and glucose homeostasis.

Synonyms: Air8 | NP33 | Phosphoprotein NP33 | Pp30 | RP S6 | RPS6 | RS6 | S6 | P62753

ID gène: 6194

UniProt: P62753

Pathways: Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly