IL1RN anticorps (AA 26-177)
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- Antigène Voir toutes IL1RN Anticorps
- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
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Épitope
- AA 26-177
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL1RN est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Fonction
- Rabbit IgG polyclonal antibody for Interleukin-1 receptor antagonist protein(IL1RN) detection. Tested with WB, ELISA in Human.
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Interleukin-1 receptor antagonist protein(IL1RN) detection. Tested with WB, ELISA in Human.
Gene Name: interleukin 1 receptor antagonist
Protein Name: Interleukin-1 receptor antagonist protein - Purification
- Immunogen affinity purified.
- Immunogène
- E. coli-derived human IL1RA recombinant protein (Position: R26-E177). Human IL1RA shares 77% and 75.5% amino acid (aa) sequence identity with mouse and rat IL1RA, respectively.
- Isotype
- IgG
- Top Product
- Discover our top product IL1RN Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signaling." dans: Pain, Vol. 155, Issue 12, pp. 2618-29, (2015) (PubMed).
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TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signaling." dans: Pain, Vol. 155, Issue 12, pp. 2618-29, (2015) (PubMed).
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- Antigène
- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
- Autre désignation
- IL1RN (IL1RN Produits)
- Synonymes
- anticorps DIRA, anticorps ICIL-1RA, anticorps IL-1RN, anticorps IL-1ra, anticorps IL-1ra3, anticorps IL1F3, anticorps IL1RA, anticorps IRAP, anticorps MVCD4, anticorps IRAP1, anticorps IL1RN, anticorps IL-1RA, anticorps F630041P17Rik, anticorps interleukin 1 receptor antagonist, anticorps interleukin 1 receptor antagonist-like, anticorps IL1RN, anticorps Il1rn, anticorps IL1RNL
- Sujet
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The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Synonyms: Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor, Anakinra, IL1RN, IL1F3, IL1RA - ID gène
- 3557
- UniProt
- P18510
- Pathways
- Signalisation NF-kappaB, Hormone Transport, Cancer Immune Checkpoints
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