TIMP1 anticorps (AA 24-207)

N° du produit ABIN5519064

Détail du produit anti-TIMP1 anticorps

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Épitope: AA 24-207

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit IgG polyclonal antibody for TIMP1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for TIMP1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
Gene Name: TIMP metallopeptidase inhibitor 1
Protein Name: Metalloproteinase inhibitor 1

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived huamn TIMP1 recombinant protein (Position: C24-A207).

Isotype: IgG

Information d'application

Indications d'application: Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-TIMP1 (ABIN5519064)

Liu, Liu, Tan, Tang, Long, Li, Liang, Chu, Yang: "Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats." dans: Molecular medicine reports, Vol. 16, Issue 6, pp. 8953-8963, (2018) (PubMed).

"Retraction: Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction." dans: PLoS ONE, Vol. 13, Issue 2, pp. e0192465, (2018) (PubMed).

Wang, Jiang, Xue: "Recombinant human endostatin reduces hypertrophic scar formation in rabbit ear model through down-regulation of VEGF and TIMP-1." dans: African health sciences, Vol. 16, Issue 2, pp. 542-53, (2017) (PubMed).

Yang, Luo, Zhu, Zhou, Wang, Xue, Zhang, Cai, Chen, Ma, Chen, Wang, Luo, Liu, Zhao: "Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo." dans: Frontiers in pharmacology, Vol. 8, pp. 929, (2017) (PubMed).

Chen, Zhang, Ma, Huang, Shao, Wu, Wang: "Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction." dans: PLoS ONE, Vol. 10, Issue 11, pp. e0143868, (2016) (PubMed).

Fan, Jiang, Li, Fang, Xu, Zheng: "MMP-1/2 and TIMP-1/2 expression levels, and the levels of collagenous and elastic fibers correlate with disease progression in a hamster model of tongue cancer." dans: Oncology letters, Vol. 11, Issue 1, pp. 63-68, (2016) (PubMed).

Di, Nie, Chen: "Matrix metalloproteinase-9 and vascular endothelial growth factor expression change in experimental retinal neovascularization." dans: International journal of ophthalmology, Vol. 9, Issue 6, pp. 804-8, (2016) (PubMed).

Deng, Ling, Liu, Zhao, Lv: "Decreased expression of matrix metalloproteinase-1 in the maternal umbilical serum, trophoblasts and decidua leads to preeclampsia." dans: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 992-998, (2015) (PubMed).

Yin, Li, Gao, Li, Li: "Andrographolide plays an important role in bleomycin-induced pulmonary fibrosis treatment." dans: International journal of clinical and experimental medicine, Vol. 8, Issue 8, pp. 12374-81, (2015) (PubMed).

Xu, Dai, Liu, Liu, Song, Li, Chen, Lin: "Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis." dans: Experimental and therapeutic medicine, Vol. 8, Issue 4, pp. 1065-1074, (2014) (PubMed).

Zhong, Wang, Jian: "Expression of matrix metalloproteinases-8 and -9 and their tissue inhibitor in the condyles of diabetic rats with mandibular advancement." dans: Experimental and therapeutic medicine, Vol. 8, Issue 5, pp. 1357-1364, (2014) (PubMed).

Ma, Ma, Ma, Sun, Yu, Wang, Li, Ding: "The Effects of Uygur Herb Hyssopus officinalis L. on the Process of Airway Remodeling in Asthmatic Mice." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 710870, (2014) (PubMed).

Li, Liu, Zhang, Zhu, He, Xiao: "Effects of augmentation of liver regeneration recombinant plasmid on rat hepatic fibrosis." dans: World journal of gastroenterology, Vol. 11, Issue 16, pp. 2438-43, (2005) (PubMed).

Yang, Xie, Geng, Luo, Han, Cheng: "Effect of Danshao Huaxian capsule on expression of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in fibrotic liver of rats." dans: World journal of gastroenterology, Vol. 11, Issue 32, pp. 4953-6, (2005) (PubMed).

Détails sur TIMP1

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Autre désignation: TIMP1 (TIMP1 Produits)

Synonymes: anticorps TIMP-1, anticorps TIMP1, anticorps DKFZp468A0912, anticorps CLGI, anticorps EPA, anticorps EPO, anticorps HCI, anticorps TIMP, anticorps Timp, anticorps Clgi, anticorps TIMP metallopeptidase inhibitor 1, anticorps tissue inhibitor of metalloproteinase 1, anticorps TIMP1, anticorps Timp1

Sujet: TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. TIMP was found to be located about 22 cM proximal to OTC (300461).

Synonyms: Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP

ID gène: 7076

UniProt: P01033