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PDCD1LG2 anticorps

PDCD1LG2 Reactivité: Humain FACS, IHC Hôte: Souris Monoclonal 24F-10C12 unconjugated
N° du produit ABIN5526895
  • Antigène Voir toutes PDCD1LG2 Anticorps
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    Reactivité
    • 75
    • 31
    • 10
    • 3
    Humain
    Hôte
    • 47
    • 31
    • 18
    • 1
    Souris
    Clonalité
    • 49
    • 45
    • 1
    Monoclonal
    Conjugué
    • 51
    • 11
    • 10
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PDCD1LG2 est non-conjugé
    Application
    • 49
    • 46
    • 38
    • 29
    • 16
    • 11
    • 10
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC)
    Specificité
    The mouse monoclonal antibody 24F.10C12 recognizes an extracellular epitope of CD273 / PD-L2 (also known as B7-DC), a 25 kDa type I transmembrane protein expressed by dendritic cells, activated monocytes and T cells, heart, first trimester placenta, lung and liver, as well as in Hodgkin´s lymphoma cells and primary mediastinal B cell lymphoma (PMBL).
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    human CD273 cDNA
    Clone
    24F-10C12
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product PDCD1LG2 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    Autre désignation
    CD273 / PD-L2 (PDCD1LG2 Produits)
    Synonymes
    anticorps PDL2, anticorps B7DC, anticorps Btdc, anticorps CD273, anticorps PD-L2, anticorps PDCD1L2, anticorps bA574F11.2, anticorps B7-DC, anticorps F730015O22Rik, anticorps programmed cell death 1 ligand 2, anticorps PDCD1LG2, anticorps Pdcd1lg2
    Sujet
    Programmed cell death 1 ligand 2,CD273 / PD-L2 (programmed death ligand-1), also known as B7-DC, is a member of the B7 family of regulatory proteins. It costimulates the proliferation of T cells, and mediates IFN gamma production. Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses. When interacting with CD279, it can act as a coinhibitor of the T cell function. CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.,PDCD1LG2, B7DC, Btdc, PDL2, PDCD1L2, bA574F11.2, Butyrophilin, B7-DC,
    ID gène
    80380
    UniProt
    Q9BQ51
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