NG2 anticorps (PE)

N° du produit ABIN5526900

Détail du produit anti-NG2 anticorps (PE)

Antigène: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NG2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: The mouse monoclonal antibody 7.1 recognizes an extracellular epitope of NG2, the melanoma-associated chondroitin sulfate proteoglycan 4 of Mw approximately 220-300 kDa.

Réactivité croisée (Details): Human

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Human bone marrow stromal cells infected with SV-40

Clone: 7-1

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Commentaires:

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur NG2

Antigène: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Autre désignation: NG2 / Chondroitin sulfate proteoglycan 4 (MCSP Produits)

Synonymes: anticorps HMW-MAA, anticorps MCSP, anticorps MCSPG, anticorps MEL-CSPG, anticorps MSK16, anticorps NG2, anticorps 4732461B14Rik, anticorps AN2, anticorps Ng2, anticorps HSMCSGEN1, anticorps MCS, anticorps chondroitin sulfate proteoglycan 4, anticorps sperm mitochondria associated cysteine rich protein, anticorps CSPG4, anticorps Cspg4, anticorps SMCP

Sujet: Chondroitin sulfate proteoglycan 4,NG2 / chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.,Chondroitin sulfate proteoglycan 4, MSK16, CSPG4, MCSP

ID gène: 1464

UniProt: Q6UVK1

Pathways: Glycosaminoglycan Metabolic Process