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NG2 anticorps (PE)

MCSP Reactivité: Humain FACS Hôte: Souris Monoclonal 7-1 PE
N° du produit ABIN5526900
  • Antigène Voir toutes NG2 (MCSP) Anticorps
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Reactivité
    • 45
    • 23
    • 17
    • 1
    Humain
    Hôte
    • 42
    • 14
    Souris
    Clonalité
    • 32
    • 23
    • 1
    Monoclonal
    Conjugué
    • 28
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp NG2 est conjugé à/à la PE
    Application
    • 31
    • 20
    • 10
    • 10
    • 8
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody 7.1 recognizes an extracellular epitope of NG2, the melanoma-associated chondroitin sulfate proteoglycan 4 of Mw approximately 220-300 kDa.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    Human bone marrow stromal cells infected with SV-40
    Clone
    7-1
    Isotype
    IgG1
    Top Product
    Discover our top product MCSP Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Autre désignation
    NG2 / Chondroitin sulfate proteoglycan 4 (MCSP Produits)
    Synonymes
    anticorps HMW-MAA, anticorps MCSP, anticorps MCSPG, anticorps MEL-CSPG, anticorps MSK16, anticorps NG2, anticorps 4732461B14Rik, anticorps AN2, anticorps Ng2, anticorps HSMCSGEN1, anticorps MCS, anticorps chondroitin sulfate proteoglycan 4, anticorps sperm mitochondria associated cysteine rich protein, anticorps CSPG4, anticorps Cspg4, anticorps SMCP
    Sujet
    Chondroitin sulfate proteoglycan 4,NG2 / chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.,Chondroitin sulfate proteoglycan 4, MSK16, CSPG4, MCSP
    ID gène
    1464
    UniProt
    Q6UVK1
    Pathways
    Glycosaminoglycan Metabolic Process
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