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PVRL1 anticorps (PE)

PVRL1 Reactivité: Humain FACS Hôte: Souris Monoclonal R1-302 PE
N° du produit ABIN5526902
  • Antigène Voir toutes PVRL1 Anticorps
    PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
    Reactivité
    • 39
    • 26
    • 26
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 31
    • 8
    Souris
    Clonalité
    • 34
    • 5
    Monoclonal
    Conjugué
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PVRL1 est conjugé à/à la PE
    Application
    • 32
    • 13
    • 13
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody R1.302 recognizes an extracellular epitope on CD111 (also known as Nectin 1), a 75 kDa type I transmembrane glycoprotein broadly expressed on endothelial cells, epithelial cells, neuronal cells, megakaryocytes, and CD34-positive stem cells.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    NIH/3T3 cells transfected with human CD111
    Clone
    R1-302
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product PVRL1 Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
    Autre désignation
    CD111 (PVRL1 Produits)
    Synonymes
    anticorps CD111, anticorps CLPED1, anticorps ED4, anticorps HIgR, anticorps HVEC, anticorps OFC7, anticorps PRR, anticorps PRR1, anticorps PVRR, anticorps PVRR1, anticorps SK-12, anticorps nectin-1, anticorps prr1, anticorps PVRL1, anticorps pvrl1, anticorps AI835281, anticorps AW549174, anticorps Cd111, anticorps HveC, anticorps cd111, anticorps cd112, anticorps clped1, anticorps ed4, anticorps higr, anticorps hveb, anticorps hvec, anticorps nectin-2, anticorps ofc7, anticorps prr, anticorps prr2, anticorps pvrl2, anticorps pvrl2.L, anticorps pvrr, anticorps pvrr1, anticorps pvrr2, anticorps sk-12, anticorps nectin cell adhesion molecule 1, anticorps nectin-1, anticorps Poliovirus receptor-related protein 1, anticorps poliovirus receptor-related 1 (herpesvirus entry mediator C), anticorps nectin cell adhesion molecule 2 L homeolog, anticorps NECTIN1, anticorps LOC100145553, anticorps pvrl1, anticorps nectin1, anticorps Nectin1, anticorps PVRL1, anticorps nectin2.L
    Sujet
    Nectin cell adhesion molecule 1,CD111, also known as nectin-1, is a calcium-independent cell-cell adhesion transmembrane glycoprotein involved in organization of adherens junctions and tight junctions in epithelial and endothelial cells. It also serves as a target molecule for entry of herpes simplex virus (HSV-1, HSV-2) and pseudorabies virus (PRV) into epithelial and neuronal cells. CD111 is connected with actin cytoskeleton through afadin. Mutations in the gene for CD111 cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.,NECTIN1, ED4, HIgR, HV1S, HVEC, OFC7, PRR1, PVRR, CD111, PVRL1, PVRR1, SK-12, CLPED1
    ID gène
    5818
    UniProt
    Q15223
    Pathways
    Cell-Cell Junction Organization
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