Tissue factor anticorps

N° du produit ABIN5526905

Détail du produit anti-Tissue factor anticorps

Antigène: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Tissue factor est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: The mouse monoclonal antibody HTF-1, also known as HTF1-7B8, recognizes an extracellular epitope of CD142 (tissue factor, coagulation factor III), a type I glycoprotein expressed on endothelial cells, monocytes, macrophages, and platelets upon induction by inflammatory mediators, and expressed constitutively by some tumors, the vasculature, placenta, kidney, and central nervous system.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Human brain tissue factor (CD142)

Clone: HTF-1

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 3-12 μg/mL.
Western blotting: Reducing conditions preferred.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur Tissue factor

Antigène: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Autre désignation: CD142 (F3 Produits)

Synonymes: anticorps CD142, anticorps TF, anticorps TFA, anticorps PRO1557, anticorps PRO2086, anticorps TFQTL1, anticorps f3, anticorps AA409063, anticorps Cf-3, anticorps Cf3, anticorps tf, anticorps zgc:112151, anticorps coagulation factor III, tissue factor, anticorps transferrin, anticorps coagulation factor IIIa, anticorps coagulation factor III, anticorps tissue factor, anticorps coagulation factor IIIb, anticorps coagulation factor III (thromboplastin, tissue factor) S homeolog, anticorps F3, anticorps TF, anticorps f3a, anticorps tf, anticorps f3b, anticorps f3.S

Sujet: Coagulation factor III, tissue factor,CD142, also known as coagulation factor III, tissue thromboplastin, and tissue factor. It is a transmembrane glycoprotein, which enables cells to initiate the blood coagulation cascades, and functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. It is the only one factor in the coagulation pathway for which a congenital deficiency has not been described.,F3, tissue factor, tissue thromboplastin, coagulation factor III, TF, TFA

ID gène: 2152

UniProt: P13726

Pathways: Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling