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GREM1 anticorps (C-Term)

GREM1 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5531272
  • Antigène Voir toutes GREM1 Anticorps
    GREM1 (Gremlin 1 (GREM1))
    Épitope
    • 19
    • 15
    • 14
    • 9
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-175, C-Term
    Reactivité
    • 77
    • 43
    • 22
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 83
    • 8
    • 1
    Lapin
    Clonalité
    • 84
    • 8
    Polyclonal
    Conjugué
    • 37
    • 13
    • 11
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GREM1 est non-conjugé
    Application
    • 78
    • 42
    • 29
    • 13
    • 13
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogène
    This GREMLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the C-terminal region of mouse GREMLIN.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GREM1 Anticorps primaire
  • Indications d'application
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    GREM1 (Gremlin 1 (GREM1))
    Autre désignation
    GREMLIN (GREM1 Produits)
    Synonymes
    anticorps grem1, anticorps MGC136702, anticorps zgc:136702, anticorps GREM1, anticorps drm, anticorps pig2, anticorps dand2, anticorps ihg-2, anticorps gremlin, anticorps Cktsf1b1, anticorps Drm, anticorps Grem, anticorps ld, anticorps gremlin-1, anticorps CKTSF1B1, anticorps DAND2, anticorps DRM, anticorps GREMLIN, anticorps IHG-2, anticorps cktsf1b1, anticorps gremlin 1a, DAN family BMP antagonist, anticorps gremlin 1, DAN family BMP antagonist, anticorps gremlin 1, anticorps gremlin 1, DAN family BMP antagonist L homeolog, anticorps grem1a, anticorps GREM1, anticorps LOC662541, anticorps grem1, anticorps Grem1, anticorps grem1.L
    Sujet
    GREMLIN is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth.
    Poids moléculaire
    21 kDa
    ID gène
    23892
    UniProt
    O70326
    Pathways
    Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location
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