GRM8 anticorps (C-Term)
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- Antigène Voir toutes GRM8 Anticorps
- GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
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Épitope
- AA 852-882, C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GRM8 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- Immunogène
- This Metabotropic Glutamate Receptor 8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 852-882 amino acids from the C-terminal region of human Metabotropic Glutamate Receptor 8.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GRM8 Anticorps primaire
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- Indications d'application
- For WB starting dilution is: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
- Autre désignation
- Metabotropic Glutamate Receptor 8 (GRM8 Produits)
- Synonymes
- anticorps mGluR8, anticorps GRM8, anticorps MGLUR8, anticorps GLUR8, anticorps GPRC1H, anticorps mGlu8, anticorps A230002O04, anticorps Gprc1h, anticorps Glur8, anticorps Mglur8, anticorps mGluR8b, anticorps mGlur, anticorps glutamate metabotropic receptor 8, anticorps metabotropic glutamate receptor 8, anticorps glutamate receptor, metabotropic 8, anticorps GRM8, anticorps MGLUR8, anticorps LOAG_14062, anticorps Grm8
- Sujet
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
- Poids moléculaire
- 102 kDa
- ID gène
- 2918
- UniProt
- O00222
- Pathways
- cAMP Metabolic Process, Synaptic Membrane
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