This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This PADI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-586 amino acids from the C-terminal region of human PADI2.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
PADI2
(Peptidyl Arginine Deiminase, Type II (PADI2))
anticorps PADI2, anticorps PAD-H19, anticorps PAD2, anticorps PDI2, anticorps Pdi, anticorps Pdi2, anticorps mKIAA0994, anticorps peptidyl arginine deiminase 2, anticorps peptidyl arginine deiminase, type II, anticorps protein-arginine deiminase type-2, anticorps peptidyl arginine deiminase, type II S homeolog, anticorps PADI2, anticorps padi2, anticorps LOC100357368, anticorps padi2.S, anticorps Padi2
Sujet
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq].