This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This HERC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human HERC3.
HERC3
Reactivité: Humain
Hôte: Lapin
Polyclonal
FITC
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
anticorps 5730409F18Rik, anticorps AI646603, anticorps mKIAA0032, anticorps HECT and RLD domain containing E3 ubiquitin protein ligase 3, anticorps HECT and RLD domain containing E3 ubiquitin protein ligase 3 L homeolog, anticorps probable E3 ubiquitin-protein ligase HERC3, anticorps hect domain and RLD 3, anticorps HERC3, anticorps herc3.L, anticorps herc3, anticorps LOC100539754, anticorps LOC100563151, anticorps Herc3
Sujet
HERC3 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).