CDH6 anticorps (C-Term)

N° du produit ABIN5534054

Détail du produit anti-CDH6 anticorps

Antigène: CDH6 (K-Cadherin (CDH6))

Épitope: AA 665-695, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDH6 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This K Cadherin (CDH6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-695 amino acids from the C-terminal region of human K Cadherin (CDH6).

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CDH6

Antigène: CDH6 (K-Cadherin (CDH6))

Autre désignation: K Cadherin (CDH6 Produits)

Synonymes: anticorps KCAD, anticorps K-cadherin, anticorps cad6, anticorps cadherin-6, anticorps CAD6, anticorps c-cad6B, anticorps cadherin 6, anticorps Cdh6, anticorps CDH6

Sujet: CDH6 is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of the CDH6 gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.

Poids moléculaire: 88 kDa

ID gène: 1004

UniProt: P55285

Pathways: Cell-Cell Junction Organization