Cofilin 2 anticorps (N-Term)

N° du produit ABIN5534069

Détail du produit anti-Cofilin 2 anticorps

Antigène: Cofilin 2 (CFL2)

Épitope: AA 25-54, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cofilin 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CFL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human CFL2.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Cofilin 2

Antigène: Cofilin 2 (CFL2)

Autre désignation: CFL2 (CFL2 Produits)

Synonymes: anticorps NEM7, anticorps CFL2, anticorps zgc:77288, anticorps cf12, anticorps cofilin 2, anticorps cofilin 2 (non-muscle), anticorps cofilin 2 (muscle), anticorps cofilin 2, muscle, anticorps cofilin-2, anticorps CFL2, anticorps cfl2, anticorps Cfl2, anticorps cf12, anticorps LOC100359205

Sujet: This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 19 kDa

ID gène: 1073

UniProt: Q9Y281

Pathways: Caspase Cascade in Apoptosis