DDR2 anticorps
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- Antigène Voir toutes DDR2 Anticorps
- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DDR2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- Immunogène
- This TYRO10 antibody is generated from rabbits immunized with a his tag recombinant protein of human TYRO10.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DDR2 Anticorps primaire
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- Indications d'application
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
- Autre désignation
- TYRO10 (DDR2 Produits)
- Synonymes
- anticorps MIG20a, anticorps NTRKR3, anticorps TKT, anticorps TYRO10, anticorps AW495251, anticorps Ntrkr3, anticorps tyro10, anticorps DDR2, anticorps Tyro10, anticorps ddr2, anticorps si:ch211-193c2.1, anticorps discoidin domain receptor tyrosine kinase 2, anticorps discoidin domain receptor family, member 2, anticorps discoidin domain receptor family, member 2, like, anticorps DDR2, anticorps Ddr2, anticorps ddr2l
- Sujet
- Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane and cytoplasmic regions. There are several subclasses of RTKs and TYRO10 belongs to a novel subclass. The deduced amino acid sequence of TYRO10 has a unique extracellular region encompassing a factor VIII-like domain, not previously described for RTKs.
- Poids moléculaire
- 97 kDa
- ID gène
- 4921
- UniProt
- Q16832
- Pathways
- Signalisation RTK
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