Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Immunogène
This FRAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-128 amino acids from the Central region of human FRAT1.
FRAT1
Reactivité: Humain
WB, IF (p), IF (cc)
Hôte: Lapin
Polyclonal
AbBy Fluor® 488
Indications d'application
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Concentration
2 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
FRAT1
(Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))
anticorps FRAT1, anticorps frat1, anticorps AW060382, anticorps gbp, anticorps FRAT1, WNT signaling pathway regulator, anticorps GSK-3 binding protein FRAT1, anticorps frequently rearranged in advanced T cell lymphomas, anticorps frequently rearranged in advanced T-cell lymphomas, anticorps frequently rearranged in advanced T-cell lymphomas 1 S homeolog, anticorps FRAT1, anticorps frat1, anticorps Frat1, anticorps frat1.S
Sujet
FRAT1 belongs to the GSK-3-binding protein family. It may function in tumor progression and in lymphomagenesis. It positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. It may play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.