TDG anticorps (N-Term)
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- Antigène Voir toutes TDG Anticorps
- TDG (Thymine-DNA Glycosylase (TDG))
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Épitope
- AA 81-110, N-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TDG est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- Immunogène
- This TDG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human TDG.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product TDG Anticorps primaire
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- Indications d'application
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For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- TDG (Thymine-DNA Glycosylase (TDG))
- Autre désignation
- TDG (TDG Produits)
- Synonymes
- anticorps 5-MCDG, anticorps wu:fb44b11, anticorps zgc:110622, anticorps MGC82456, anticorps MGC89441, anticorps E130317C12Rik, anticorps JZA-3, anticorps Jza1, anticorps hTDG, anticorps thymine DNA glycosylase, anticorps thymine DNA glycosylase, tandem duplicate 1, anticorps putative g/t mismatch-specific thymine DNA glycosylase, anticorps G/T mismatch-specific thymine DNA glycosylase, anticorps thymine DNA glycosylase S homeolog, anticorps thymine-DNA glycosylase, anticorps TDG, anticorps tdg.1, anticorps Smp_149220, anticorps Tsp_05734, anticorps tdg.S, anticorps tdg, anticorps Tdg
- Sujet
- The protein TDG belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.
- Poids moléculaire
- 46 kDa
- ID gène
- 6996
- UniProt
- Q13569
- Pathways
- Réparation de l'ADN, Chromatin Binding
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