PDE11A anticorps (N-Term)

N° du produit ABIN5537471

Détail du produit anti-PDE11A anticorps

Antigène: PDE11A (phosphodiesterase 11A (PDE11A))

Épitope: AA 34-63, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE11A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PDE11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-63 amino acids from the N-terminal region of human PDE11A.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PDE11A

Antigène: PDE11A (phosphodiesterase 11A (PDE11A))

Autre désignation: PDE11A (PDE11A Produits)

Synonymes: anticorps PPNAD2, anticorps 6330414F14Rik, anticorps A630086N24Rik, anticorps Gm350, anticorps PDE11A1, anticorps si:ch211-222f23.5, anticorps PDE11A, anticorps ppnad2, anticorps Pde11a, anticorps phosphodiesterase 11A, anticorps phosphodiesterase 11a, anticorps dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, anticorps PDE11A, anticorps Pde11a, anticorps pde11a, anticorps LOC100470038

Sujet: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 105 kDa

ID gène: 50940

UniProt: Q9HCR9

Pathways: cAMP Metabolic Process