KCNK2 anticorps (AA 4-14)

N° du produit ABIN5540445

Détail du produit anti-KCNK2 anticorps

Antigène: KCNK2 (Potassium Channel, Subfamily K, Member 2 (KCNK2))

Épitope: AA 4-14

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNK2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: SASRERPGYT A

Specificité: This antibody reacts with the 47 kDa TREK-1 in Jurkat cell extract.

Purification: Protein G affinity

Immunogène: A synthetic peptide derived from the amino sequence 4-14 of human TREK-1, conjugated with KLH

Information d'application

Indications d'application: ELISA: The antibody (1:500,000 diluted) can detect the TREK-1 peptide coated on ELISA plate at 100 ng/well. Western blot: Dilute approx. 1:3,000 to detect the 47 kDa TREK-1 in Jurkat cell extract.

Restrictions: For Research Use only

Stockage

Buffer: 0.01M PBS, pH 7.4

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur KCNK2

Antigène: KCNK2 (Potassium Channel, Subfamily K, Member 2 (KCNK2))

Autre désignation: kcnk2 (KCNK2 Produits)

Synonymes: anticorps KCNK2, anticorps K2p2.1, anticorps TPKC1, anticorps TREK, anticorps TREK-1, anticorps TREK1, anticorps hTREK-1c, anticorps hTREK-1e, anticorps A430027H14Rik, anticorps AI848635, anticorps Trek-1, anticorps rTREK1d, anticorps potassium two pore domain channel subfamily K member 2, anticorps potassium channel, two pore domain subfamily K, member 2, anticorps potassium channel, subfamily K, member 2, anticorps KCNK2, anticorps kcnk2, anticorps Kcnk2

Sujet: TWIK-related potassium channel 1(TREK-1), also known as K2P2.1, is a two pore domain gated potassium channel that is involved with pain reception. TREK-1 is highly expressed in small sensory neurons and is extensively colocalized with TRPV1. TREK-1 is sensitive to noxious stimuli including extracellular pH , temperature, mechanical force, osmotic pressure and other stimuli. TREK-1 is one of the targets for pain mediator and anaesthesia drug.