PTPRT anticorps (AA 1-742)

N° du produit ABIN5540588

Détail du produit anti-PTPRT anticorps

Antigène: PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

Épitope: AA 1-742

Reactivité: Humain, Rat, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTPRT est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

Specificité: Monoclonal antibodies 3G4 and 3D7 have been directed against the extracellular domain of RPTPμ.

Purification: Purified

Immunogène: This antibody has been derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with ExG protein, secreted by NIH-3T3 transfected cells and purified with glutahione beads. The cells have been transfected using a fusion construct, termed ExG, encoding the entire ectodomain of the Human RPTPmu molecule (aa 1-742), fused COOH terminally to GST.

Clone: 3D7

Isotype: IgG2a

Information d'application

Indications d'application: Western blot. Immunoprecipitation. Immunofluorescence. Flow Cytometry.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PTPRT

Antigène: PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

Autre désignation: ptprt (PTPRT Produits)

Synonymes: anticorps RPTPrho, anticorps RPTP-rfo, anticorps mKIAA0283, anticorps protein tyrosine phosphatase, receptor type T, anticorps protein tyrosine phosphatase, receptor type, T, anticorps PTPRT, anticorps Ptprt

Sujet: Receptor-like protein tyrosine phosphatases (RPTPs) represent a new family of transmembrane proteins that are thought to transduce external signals by dephosphorylating phosphotyrosine residues on intracellular substrates. RPTPμ is a prototypic receptor-like protein-tyrosine phosphatase (RPTP) that mediates homotypic cell-cell interactions. Intracellularly, RPTPμ consists of a relatively large juxtamembrane region (about 150 amino acids) and two conserved phosphatase domains. As in most RPTPs, the first (membrane-proximal) PTP domain of RPTPμ is catalytically active, whereas its second (C-terminal) domain is inactive. RPTPμ is involved in cell-cell adhesion through homophilic interactions and may also play a key role in signal transduction and growth control.

UniProt: O14522