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Rituximab anticorps (HRP)

EIA Hôte: Rat Monoclonal MB2 A4 HRP
N° du produit ABIN5541687
  • Antigène Tous les produits Rituximab
    Rituximab
    Reactivité
    Veuillez nous consulter SVP
    Hôte
    • 3
    • 2
    Rat
    Clonalité
    • 5
    Monoclonal
    Conjugué
    • 3
    • 2
    Cet anticorp Rituximab est conjugé à/à la HRP
    Application
    • 3
    • 2
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    Specificité
    This antibody specifically recognises the idiotypic determinants expressed by the Rituximab humanised monoclonal antibody. This antibody does not recognise other CD20 antibodies. It has been used to detect Rituximab bound to the surface of the Raji B cell line, however detection of Rituximab bound 'in vivo' to B-CLL cells has not been demonstrated. It is possible that complement deposition on Rituximab opsonised cells inhibits binding of the anti-Rituximab antibody to cell bound Rituximab (3). Clone MB2A4 has been used in ELISA assays to monitor the levels of rituximab in patient serum following therapy (4,5).
    Purification
    Affinity chromatography on Protein G
    Immunogène
    F(ab)2 fragment of Rituximab
    Clone
    MB2 A4
    Isotype
    IgG2a
  • Indications d'application
    ELISA: 1/20000-1/20000.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
    Date de péremption
    12 months
  • Antigène
    Rituximab
    Abstract
    Rituximab Produits
    Classe de substances
    Antibody
    Sujet
    Rituximab is a therapeutic reagent directed against the human CD20 cell surface antigen.
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