Keratan Sulfate anticorps

N° du produit ABIN5541885

Détail du produit anti-Keratan Sulfate anticorps

Antigène: Keratan Sulfate (KS)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Keratan Sulfate est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This Monoclonal 4B3/D10 antibody is specific for Keratan Sulfate Glycosaminoglycan chains. Preliminary results, based on western blot analysis of keratan sulfate from different sources, indicate that mAb 4B3/10 is specific for keratan sulfate from articular cartilage and shows only minimal if any cross-reac-tivity with keratan sulfate from intervertebral disc. This is in contrast to the epitope recognized by the known mAb 5D4, that recognizes a widely distributed keratan sulfate epitope. Therefore, in addition to appliations in Immunochemistry and Immunohistochemistry, the mAb 4B3/D10 is well suited for detecting keratan sulfate fragments released during human inflammatory or degenerative joint diseases into synovial fluid and serum. Species: Human.

Purification: Protein G Chromatography

Immunogène: Purified Human Aggrecan

Clone: 4B3-D10

Isotype: IgG1

Information d'application

Indications d'application: ELISA (less than 1 μg/mL). Western blot (1 μg/mL). Immunohistochemistry (1 μg/mL).

Restrictions: For Research Use only

Stockage

Buffer: 50 mM TRIS pH 7,4

Stock: 4 °C,-20 °C

Stockage commentaire: Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Keratan Sulfate

Antigène: Keratan Sulfate (KS)

Autre désignation: keratan-sulfate (KS Produits)

Sujet: Aggrecan is the major proteoglycan of human articular car-tilage. The core protein is substituted by a number of keratan sulfate and chondroitin sulfate glycosaminoglycan chains. Whereas chondroitin sulfate is widely distributed throughout the body, keratan sulfate is primarily expressed in cartilage (joints, trachea, intervertebral discs) and cornea.