PRPS1 anticorps (AA 1-318)

N° du produit ABIN5542153

Détail du produit anti-PRPS1 anticorps

Antigène: PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

Épitope: AA 1-318

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRPS1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Immunocytochemistry (ICC)

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human PRPS1 (1-318aa) purified from E. coli

Clone: AT1E11

Isotype: IgG2a

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis and Immunofluorescence / Immnunocytochemistry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PRPS1

Antigène: PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

Autre désignation: prps1 (PRPS1 Produits)

Synonymes: anticorps ARTS, anticorps CMTX5, anticorps DFN2, anticorps DFNX1, anticorps PPRibP, anticorps PRS-I, anticorps PRSI, anticorps 2310010D17Rik, anticorps C76571, anticorps C76678, anticorps Prps-1, anticorps cb96, anticorps prps1, anticorps wu:fa18f03, anticorps wu:fb33h12, anticorps wu:fd26g08, anticorps zgc:55299, anticorps zgc:76932, anticorps arts, anticorps cmtx5, anticorps ppribp, anticorps prsi, anticorps fc64g03, anticorps im:6909503, anticorps wu:fc64g03, anticorps zgc:153331, anticorps phosphoribosyl pyrophosphate synthetase 1, anticorps phosphoribosyl pyrophosphate synthetase 1A, anticorps phosphoribosyl pyrophosphate synthetase 1 L homeolog, anticorps phosphoribosyl pyrophosphate synthetase 1B, anticorps PRPS1, anticorps Prps1, anticorps prps1a, anticorps prps1.L, anticorps prps1b

Sujet: PRPS1 is an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. A mutation in PRPS1 may result in PRPS superactivity, a disease characterized by gout and the overproduction of purine nucleotides, uric acid and PRPP. PRPS1 mutations can also lead to a reduction in PRPS1 activity resulting in ARTS syndrome or CMTX5 (Charcot-Marie-Tooth disease X-linked recessive type 5).

UniProt: P60891

Pathways: Ribonucleoside Biosynthetic Process