ANAPC10 anticorps (AA 1-185)
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- Antigène Voir toutes ANAPC10 Anticorps
- ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))
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Épitope
- AA 1-185
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ANAPC10 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Fonction
- ANAPC10 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human ANAPC10 (AA: 1-185) expressed in E. Coli.
- Clone
- 8F1D10
- Isotype
- IgG1
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Antigène
- ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))
- Autre désignation
- ANAPC10 (ANAPC10 Produits)
- Sujet
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Description: ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1, MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1, MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1, MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).
Aliases: DOC1, APC10
- Poids moléculaire
- 21.3kDa
- ID gène
- 10393
- HGNC
- 3417
- UniProt
- Q9UM13
- Pathways
- M Phase
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