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BIN1 anticorps (AA 189-398)

BIN1 Reactivité: Humain WB, ELISA, FACS Hôte: Souris Monoclonal 3B6A4 unconjugated
N° du produit ABIN5542281
  • Antigène Voir toutes BIN1 Anticorps
    BIN1 (Bridging Integrator 1 (BIN1))
    Épitope
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 189-398
    Reactivité
    • 44
    • 24
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 31
    • 12
    • 1
    Souris
    Clonalité
    • 31
    • 13
    Monoclonal
    Conjugué
    • 35
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BIN1 est non-conjugé
    Application
    • 32
    • 16
    • 15
    • 10
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Fonction
    BIN1 Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human BIN1 (AA: 189-398) expressed in E. Coli.
    Clone
    3B6A4
    Isotype
    IgG2b
    Top Product
    Discover our top product BIN1 Anticorps primaire
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    BIN1 (Bridging Integrator 1 (BIN1))
    Autre désignation
    BIN1 (BIN1 Produits)
    Sujet

    Description: This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

    Aliases: AMPH2, AMPHL, SH3P9

    Poids moléculaire
    64.7kDa
    ID gène
    274
    HGNC
    274
    UniProt
    O00499
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