HDAC4 anticorps (AA 456-592)

N° du produit ABIN5542325

Détail du produit anti-HDAC4 anticorps

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Épitope: AA 456-592

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HDAC4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Fonction: HDAC4 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human HDAC4 (AA: 456-592) expressed in E. Coli.

Clone: 5E4A5

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur HDAC4

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Autre désignation: HDAC4 (HDAC4 Produits)

Sujet:

Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Aliases: HD4, AHO3, BDMR, HDACA, HA6116, HDAC-4, HDAC-A

Poids moléculaire: 119kDa

ID gène: 9759

HGNC: 9759

UniProt: P56524

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process