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LDLR anticorps (AA 22-150)

LDLR Reactivité: Humain ELISA, FACS, IHC Hôte: Souris Monoclonal 1B10H10 unconjugated
N° du produit ABIN5542334
  • Antigène Voir toutes LDLR Anticorps
    LDLR (Low Density Lipoprotein Receptor (LDLR))
    Épitope
    • 16
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-150
    Reactivité
    • 80
    • 45
    • 32
    • 17
    • 16
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 69
    • 12
    • 5
    Souris
    Clonalité
    • 68
    • 18
    Monoclonal
    Conjugué
    • 44
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LDLR est non-conjugé
    Application
    • 59
    • 34
    • 25
    • 18
    • 13
    • 8
    • 8
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)
    Fonction
    LDLR Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human LDLR (AA: 22-150) expressed in E. Coli.
    Clone
    1B10H10
    Isotype
    IgG1
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène
    LDLR (Low Density Lipoprotein Receptor (LDLR))
    Autre désignation
    LDLR (LDLR Produits)
    Synonymes
    anticorps FH, anticorps FHC, anticorps LDLCQ2, anticorps Hlb301, anticorps LDLRA, anticorps LDLA, anticorps LDL receptor-2, anticorps fhc, anticorps ldlcq2, anticorps ldlr, anticorps ldlr2-a, anticorps LDL receptor 1, anticorps ldlr-a, anticorps ldlr-b, anticorps low density lipoprotein receptor, anticorps low density lipoprotein receptor a, anticorps low density lipoprotein receptor S homeolog, anticorps low density lipoprotein receptor L homeolog, anticorps LDLR, anticorps Ldlr, anticorps ldlra, anticorps ldlr.S, anticorps ldlr.L
    Sujet

    Description: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.r

    Aliases: FH, FHC, LDLCQ2

    Poids moléculaire
    95.4kDa
    ID gène
    3949
    HGNC
    3949
    UniProt
    P01130
    Pathways
    Hepatitis C, Lipid Metabolism
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