PKN1 anticorps (AA 442-620)

N° du produit ABIN5542353

Détail du produit anti-PKN1 anticorps

Antigène: PKN1 (Protein Kinase N1 (PKN1))

Épitope: AA 442-620

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PKN1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: PKN1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PKN1 (AA: 442-620) expressed in E. Coli.

Clone: 4H10B1

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur PKN1

Antigène: PKN1 (Protein Kinase N1 (PKN1))

Autre désignation: PKN1 (PKN1 Produits)

Synonymes: anticorps DBK, anticorps PAK-1, anticorps PAK1, anticorps PKN, anticorps PKN-ALPHA, anticorps PRK1, anticorps PRKCL1, anticorps F730027O18Rik, anticorps Pkn, anticorps Prkcl1, anticorps Stk3, anticorps PKN1, anticorps 3-2, anticorps CG2049, anticorps CG2055, anticorps CT6637, anticorps CT6660, anticorps DPKN, anticorps Dmel\\CG2049, anticorps Dpkn, anticorps PRK2, anticorps Pk45C, anticorps Pk?3, anticorps dPKN, anticorps l(2)06736, anticorps l(2)45Ca, anticorps v(2)rG232, anticorps protein kinase N1, anticorps protein kinase N1b, anticorps Protein kinase N, anticorps PKN1, anticorps Pkn1, anticorps pkn1b, anticorps pkn1, anticorps Pkn

Sujet:

Description: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Aliases: DBK, PKN, PAK1, PRK1, PAK-1, PRKCL1, PKN-ALPHA

Poids moléculaire: 104kDa

ID gène: 5585

HGNC: 5585

UniProt: Q16512