alpha Adducin anticorps (AA 1-193)

N° du produit ABIN5542416

Détail du produit anti-alpha Adducin anticorps

Antigène: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Épitope: AA 1-193

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp alpha Adducin est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Fonction: ADD1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human ADD1 (AA: 1-193) expressed in E. Coli.

Clone: 5D4H1

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur alpha Adducin

Antigène: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Autre désignation: ADD1 (ADD1 Produits)

Synonymes: anticorps ADDA, anticorps AI256389, anticorps alpha-adducin, anticorps bZ1H20.1, anticorps cb787, anticorps zgc:158352, anticorps add2, anticorps adda, anticorps add1-a, anticorps ADD1, anticorps adducin 1, anticorps adducin 1 (alpha), anticorps adducin 1 S homeolog, anticorps ADD1, anticorps Add1, anticorps add1, anticorps add1.S

Sujet:

Description: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.

Aliases: ADDA

Poids moléculaire: 81kDa

ID gène: 118

HGNC: 118

UniProt: P35611

Pathways: Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling