JARID2 anticorps (AA 1097-1246)

N° du produit ABIN5542458

Détail du produit anti-JARID2 anticorps

Antigène: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Épitope: AA 1097-1246

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp JARID2 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: JARID2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human JARID2 (AA: 1097-1246) expressed in E. Coli.

Clone: 7H1B3

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur JARID2

Antigène: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Autre désignation: JARID2 (JARID2 Produits)

Synonymes: anticorps JMJ, anticorps Jmj, anticorps jumonji, anticorps JARID2, anticorps jarid2, anticorps jmj, anticorps si:dkey-211c3.1, anticorps Jumonji, anticorps jarid2-a, anticorps jarid2-b, anticorps jarid2.S, anticorps jarid2b, anticorps jumonji and AT-rich interaction domain containing 2, anticorps jumonji, AT rich interactive domain 2, anticorps jumonji, AT rich interactive domain 2a, anticorps jumonji, AT rich interactive domain 2b, anticorps jumonji and AT-rich interaction domain containing 2 L homeolog, anticorps JARID2, anticorps Jarid2, anticorps jarid2a, anticorps jarid2, anticorps jarid2b, anticorps jarid2.L

Sujet:

Description: This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.

Aliases: JMJ

Poids moléculaire: 139kDa

ID gène: 3720

HGNC: 3720

UniProt: Q92833

Pathways: Chromatin Binding