UCP2 anticorps (AA 1-309)

N° du produit ABIN5542465

Détail du produit anti-UCP2 anticorps

Antigène: UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))

Épitope: AA 1-309

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp UCP2 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: UCP2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human UCP2 (AA: 1-309) expressed in E. Coli.

Clone: 3F1B9

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur UCP2

Antigène: UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))

Autre désignation: UCP2 (UCP2 Produits)

Synonymes: anticorps UCP2, anticorps DKFZp470P1633, anticorps ucp2, anticorps MGC53319, anticorps MGC75881, anticorps cb74, anticorps ATUCP2, anticorps K19M22.21, anticorps K19M22_21, anticorps uncoupling protein 2, anticorps BMIQ4, anticorps SLC25A8, anticorps UCPH, anticorps Slc25a8, anticorps mitochondrial uncoupling protein 2, anticorps uncoupling protein 2, anticorps uncoupling protein 2 (mitochondrial, proton carrier) L homeolog, anticorps uncoupling protein 2 (mitochondrial, proton carrier), anticorps uncoupling protein 1, anticorps PTRG_09289, anticorps UCP2, anticorps LOC100282746, anticorps ucp2.L, anticorps ucp2, anticorps ucp1, anticorps Ucp2

Sujet:

Description: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.

Aliases: UCPH, BMIQ4, SLC25A8

Poids moléculaire: 33.2kDa

ID gène: 7351

HGNC: 7351

UniProt: P55851

Pathways: Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Proton Transport