CBX3 anticorps (AA 1-183)

N° du produit ABIN5542474

Détail du produit anti-CBX3 anticorps

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Épitope: AA 1-183

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CBX3 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Fonction: CBX3 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CBX3 (AA: 1-183) expressed in E. Coli.

Clone: 6D1C4

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur CBX3

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Autre désignation: CBX3 (CBX3 Produits)

Synonymes: anticorps HECH, anticorps HP1-GAMMA, anticorps HP1Hs-gamma, anticorps Hp1-gamma, anticorps HP1g, anticorps M32, anticorps cbx3, anticorps cbx3a, anticorps xhp1g, anticorps wu:fb61b02, anticorps zgc:153397, anticorps chromobox 3, anticorps chromobox 3 L homeolog, anticorps chromobox protein homolog 3 pseudogene, anticorps chromobox homolog 3a (HP1 gamma homolog, Drosophila), anticorps CBX3, anticorps Cbx3, anticorps cbx3.L, anticorps LOC100355282, anticorps cbx3a

Sujet:

Description: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

Aliases: HECH, HP1-GAMMA, HP1Hs-gamma

Poids moléculaire: 20.8kDa

ID gène: 11335

HGNC: 11335

UniProt: Q13185