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MECP2 anticorps (AA 7-148)

MECP2 Reactivité: Humain WB, ELISA, IHC, FACS, ICC Hôte: Souris Monoclonal 8H4A5B9 unconjugated
N° du produit ABIN5542475
  • Antigène Voir toutes MECP2 Anticorps
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Épitope
    • 19
    • 11
    • 9
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 7-148
    Reactivité
    • 101
    • 40
    • 31
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 101
    • 6
    • 1
    Souris
    Clonalité
    • 102
    • 6
    Monoclonal
    Conjugué
    • 62
    • 10
    • 8
    • 8
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MECP2 est non-conjugé
    Application
    • 79
    • 63
    • 35
    • 29
    • 12
    • 10
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human MECP2 (AA: 7-148) expressed in E. coli.
    Clone
    8H4A5B9
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Autre désignation
    MECP2 (MECP2 Produits)
    Synonymes
    anticorps AUTSX3, anticorps MRX16, anticorps MRX79, anticorps MRXS13, anticorps MRXSL, anticorps PPMX, anticorps RS, anticorps RTS, anticorps RTT, anticorps 1500041B07Rik, anticorps BB130002, anticorps D630021H01Rik, anticorps Mbd5, anticorps WBP10, anticorps wu:fk96a04, anticorps zgc:111857, anticorps methyl-CpG binding protein 2, anticorps methyl CpG binding protein 2, anticorps methyl-CpG binding protein 2 S homeolog, anticorps MECP2, anticorps Mecp2, anticorps mecp2, anticorps mecp2.S
    Sujet

    Description: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.,

    Aliases: RS, RTS, RTT, PPMX, MRX16, MRX79, MRXSL, AUTSX3, MRXS13

    Poids moléculaire
    52.4 kDa
    ID gène
    4204
    HGNC
    4204
    Pathways
    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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